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Closing the gap: How weight loss medications help MASLD patients with type 2 diabetes.

Updated: 3 days ago


weight loss medications
Weight loss medication helping with type 2 diabetes

Metabolic dysfunction associated steatotic liver disease (MASLD) formerly known as NAFLD ,is now recognized as the most common liver condition worldwide affecting up to 1 in 4 adults.When paired with type 2 diabetes ,the risk of liver fibrosis ,cirrhosis,and cardiovascular disease increase significantly.


Weight loss remains the cornerstone of MASLD management ,but many patients struggle to achieve and maintain 7 to 10% weight reduction needed to improve liver health.


At Crabtree health ,we offer advanced research backed weight loss medications integrated into a holistic care plan to help patients lose weight ,improve liver scores, and gain control of their health.


Why Weight loss matters in MASLD and type 2 diabetes


Clinical studies Shows that weight loss of 5 to 10% can reduce liver fat inflammation and fibrosis in M ASLD. In patients with type 2 diabetes, this can also improve insulin sensitivity and reduce A1c levels.


However, lifestyle modifications alone may not be enough. Patients with diabetes face additional metabolic challenges that make weight loss difficult.


The role of GLP-1 and GIP/GL-1 one receptor agnostics


Medication’s like Semaglutide (Ozempic, and Wegovy) and tirzepatide (Mounjaro ,Zepbound )

have revolutionized weight management, showing.


  • 15 to 20% average weight loss in clinical trials

  • Reduction in in liver fat content

  • Improvement in liver stiffness, and fibrosis markers

  • Significant reduction in A1C

  • Decreased cardiovascular risk


Recent trials, including the STEP and SURMOUNT studies demonstrate that GLP-1 based therapies not only aid in weight loss, but also improve MASLD scores ,with patients experiencing improve ALT levels and reductions in liver fat Measured by MRI-PDFF.




How we can help at Crabtree Health


At Crabtree Health, we take a comprehensive physician guided approach to weight loss and MASLD management:


  • Personalized asessment :Liver ultrasound, Fibro referrals and scan comprehensive lab work

  • Medication selection :GLP -1/GIP therapy combined with lifestyle modifications

  • Ongoing monitoring : Tracking weight, A1c, liver enzymes, and non-invasive fibrosis markers

  • Nutrition counseling: practical meal plans and coaching to maximize weight loss while supporting liver health Insurance navigation : we help determine if your insurance will cover weight loss medication or discuss affordable alternatives


We work closely with each patient to optimize metabolic health, liver health, and diabetes management.


The latest research and your health


The American Association for the study of liver disease (AASLD) an American diabetes Association (ADA) now recognize GLP -1 based medication as part of comprehensive MASLD care in patients with type 2 diabetes when lifestyle interventions are insufficient.


Incorporating these researched backed therapies can be a game changer for patients who have struggled with diet alone.


Take the next step towards liver and metabolic health


If you have type 2 diabetes, and MASLD, you don’t have to navigate this journey alone. At Crabtree Health we use cutting edge treatments with compassionate care to help you lose weight, improve your liver health and regain energy.


Ready to get started


Book your free consultation here to see if we advanced weight loss medications are right for you



Final note


Your liver health matters let us help you take charge of your health with personalized , research based treatments that you go beyond just the scale.

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